Predictors of Short- and Long-term Survival in HIV-Infected Patients Admitted to the ICU: Characteristics of the Population
The mean Glasgow coma scale score was 8.9±4 in the neurologic failure admission group. Toxoplasmic encephalitis contributed 62.1% of cases in this group (59 patients/95 patients) and 16.6% of all HIV-related admissions (59 patients/354 patients). A total of 21% of neurologic admissions (20 patients/95 patients) were for intracerebral lesions other than toxoplasmic encephalitis on cerebral imaging studies, including cerebral tuberculosis (5 patients), cryptococcosis (4 patients), nocardiosis (3 patients), cerebral lymphoma (5 patients), or other intracerebral space-occupying lesions such as progressive multifocal leukoencephalitis (3 patients). Patients with predominant clinical features of meningitis accounted for 16.8% (16 patients/95 patients) of neurologic admissions, with the diagnoses being nonopportunis-tic bacterial meningitis (4 patients), tuberculous meningitis (4 patients), nocardiosis (2 patients), and cryptococcal meningitis (6 patients). Causes of heart failure included acute or subacute tuberculous pericarditis (three patients), cryptococcal pericarditis (one patient), cardiac involvement in disseminated toxoplasmosis (one patient), cardiac lymphomas (one patient), beriberi (one patient), and HIV-related dilated cardiomyopathy (nine patients).
Diagnoses in the severe sepsis group included sepsis syndrome related to bacterial septicemia (8 patients), bacterial pneumonia (18 patients), disseminated tuberculosis (4 patients), and disseminated toxoplasmosis (6 patients).
Miscellaneous causes were mainly toxic reactions to drugs, renal failure, drug overdoses, suicide attempts, and surveillance after invasive procedures.
For 11%, 21%, and 6% of the patients, no directly objective data were available concerning the weight loss (then weight loss was calculated by using ideal weight on insurance tables), the duration of HIV infection, or the duration of the antiretroviral treatment, respectively. Analyses were performed with and without these patients. No significant difference was found.