The present study provides data regarding the progression of erythropoiesis in late embryonic and early fetal swine of different breeds and uterine environments. These data indicate that the time period between Day 24 and Day 40 is indeed a critical time in the progression of erythropoiesis, since the circulating blood cell populations increase dramatically and change from primarily primitive precursors to almost entirely mature erythrocytes during this time. These data also indicate that the MS fetuses differ from WC fetuses in this process. buy diabetes drugs
Most parameters studied were generally lower in MS than in WC, except that MS fetuses had a somewhat more mature erythron. This study also indicates that the uterine environment had little overall effect on erythropoiesis in WC pigs but did affect fetal survival. The relationship of fetal weight and hematocrit/hemoglobin found for fetuses in the UHO group suggests that crowding may compromise erythropoiesis in small fetuses. However, all fetuses were not subjected to all the procedures in this study in order that a variety of procedures could be used to provide baseline information. Further studies focused on a few parameters that can be measured on every fetus are needed to fully evaluate whether abnormal erythropoiesis may be involved in fetal losses due to crowding.