A 33-year-old woman presented with a 7-month history of a solitary, well-demarcated, erythematous nodule with brown to black colored crust in the left axilla. The size increased after the patient gave stimulus to the lesion by squeezing it with her hands. There was no previous personal history of skin cancer and no other significant cutaneous or medical history was elicited. Notably she had no history of trauma, chronic axillary inflammation, immune deficiency, or exposure to artificial ionizing radiation or arsenic. There was no family history of skin cancer or other skin disease. On examination, the left axillary vault revealed a solitary, asymptomatic, erythematous nodule with brown to black colored crust measuring 1.0 x 0.8 x 1.5 cm (Fig. 1). No lymphadenopathy was appreciated.
Fig. 1. (A) Localized, tender, 1.0 x 0.8 x 0.5 cm-sized, brownish-black nodule in the axilla. (B) Close-up view of the skin lesion.
Laboratory studies including a complete blood cell count, blood chemistry, VDRL, urinalysis, chest X-ray and electrocardiogram were within normal limits or negative. Histopathologic examination showed proliferation of basaloid cells that extended into the dermis with a cyst-like enlarged structure (Fig. 2A). Peripheral palisading was prominent in many of the cellular aggregates. In the center of the cyst-like enlarged structure, the basaloid cells showed slightly enlarged, hyperchromatic nuclei and scanty amphophilic cytoplasm (Fig. 2B), and atypical cells stained negative for PAS. On immunohistochemical analysis, atypical cells stained negative for CEA, EMA and vimentin.
canadian cialis online
Fig. 2. (A) Atypical cell mass shows infiltration dermis with cyst-like enlarged structure (H&E, x 100). (B) In the center of the cyst-like enlarged structure, there are many basaloid cells with dark-staining nuclei and little cytoplasm (H&E, x 200).
Based on the results of laboratory and histopatho- logical findings, this case was diagnosed as an adenoid basal cell carcinoma. A surgical excision was performed that removed the entire lesion and no recurrence was noted. Viagra Professional